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• Activity deltas table
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Motif ID: HOX{A5,B5}.p2

Z-value: 0.998

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_9268513	2.496		A2M	alpha-2-macroglobulin
chr15_+_74218794	1.840		LOXL1	lysyl oxidase-like 1
chr15_+_74218786	1.811	NM_005576	LOXL1	lysyl oxidase-like 1
chr15_+_74218811	1.809		LOXL1	lysyl oxidase-like 1
chr12_-_91572328	1.715	NM_133504 NM_133505 NM_133506 NM_133507	DCN	decorin
chr7_-_47622127	1.684		TNS3	tensin 3
chr1_-_161193190	1.521		APOA2	apolipoprotein A-II
chrX_+_51546154	1.383	NM_001005332	MAGED1	melanoma antigen family D, 1
chrX_+_54834775	1.349	NM_014599	MAGED2	melanoma antigen family D, 2
chr13_-_110802708	1.338		COL4A1	collagen, type IV, alpha 1
chr7_+_45933096	1.336
chrX_+_135230736	1.319	NM_001159700	FHL1	four and a half LIM domains 1
chr3_-_51993955	1.291		PCBP4	poly(rC) binding protein 4
chr1_-_161193375	1.271	NM_001643	APOA2	apolipoprotein A-II
chr1_+_114522029	1.247	NM_020190	OLFML3	olfactomedin-like 3
chr2_+_30369868	1.206		YPEL5	yippee-like 5 (Drosophila)
chr13_-_46679143	1.200	NM_001872 NM_016413	CPB2	carboxypeptidase B2 (plasma)
chr2_-_88427535	1.193	NM_001443	FABP1	fatty acid binding protein 1, liver
chr12_-_56101465	1.179		ITGA7	integrin, alpha 7
chr6_+_31868775	1.157	NM_001178063	C2	complement component 2
chr4_-_114900802	1.123	NM_024590	ARSJ	arylsulfatase family, member J
chr4_-_110723334	1.093	NM_000204	CFI	complement factor I
chr6_+_29913400	1.042
chrX_+_99899388	1.027		SRPX2	sushi-repeat containing protein, X-linked 2
chr2_-_56151273	1.007	NM_001039348 NM_001039349	EFEMP1	EGF containing fibulin-like extracellular matrix protein 1
chrX_+_100333835	0.977	NM_021637	TMEM35	transmembrane protein 35
chrM_+_12283	0.967
chr12_+_53693454	0.966	NM_021640	C12orf10	chromosome 12 open reading frame 10
chr2_+_30369800	0.962		YPEL5	yippee-like 5 (Drosophila)
chr5_+_148520985	0.918	NM_014945	ABLIM3	actin binding LIM protein family, member 3
chr4_-_80994183	0.869
chr20_+_19915716	0.861		RIN2	Ras and Rab interactor 2
chr2_+_30369749	0.860	NM_001127399 NM_001127400 NM_001127401 NM_016061	YPEL5	yippee-like 5 (Drosophila)
chr19_-_50143350	0.860	NM_006270	RRAS	related RAS viral (r-ras) oncogene homolog
chrX_+_54834107	0.838	NM_177433	MAGED2	melanoma antigen family D, 2
chr2_+_8822112	0.802	NM_002166	ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr7_-_47621741	0.762	NM_022748	TNS3	tensin 3
chr22_-_50746000	0.754	NM_012401	PLXNB2	plexin B2
chr5_+_17217474	0.750	NM_006317	BASP1	brain abundant, membrane attached signal protein 1
chr4_+_41258909	0.717		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr12_-_106533810	0.701	NM_014840	NUAK1	NUAK family, SNF1-like kinase, 1
chr16_+_3115641	0.695	NM_001012632 NM_001012636	IL32	interleukin 32
chr6_+_36644236	0.678	NM_001220777 NM_078467	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr1_-_163113129	0.669		RGS5	regulator of G-protein signaling 5
chr21_-_28339405	0.663	NM_007038	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr4_+_41258895	0.662	NM_004181	UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr12_-_6798419	0.661		ZNF384	zinc finger protein 384
chr2_-_217540722	0.630		IGFBP5	insulin-like growth factor binding protein 5
chr8_-_93107881	0.624	NM_001198625 NM_001198626 NM_001198627 NM_001198631 NM_001198634 NM_001198679	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_-_149535138	0.624		PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr10_+_114136014	0.623		ACSL5	acyl-CoA synthetase long-chain family member 5
chr6_+_121756744	0.606	NM_000165	GJA1	gap junction protein, alpha 1, 43kDa
chr17_+_38599651	0.602	NM_001552	IGFBP4	insulin-like growth factor binding protein 4
chrX_+_102883647	0.598	NM_001006640	TCEAL1	transcription elongation factor A (SII)-like 1
chr12_-_9268522	0.597	NM_000014	A2M	alpha-2-macroglobulin
chr3_-_55521330	0.593	NM_003392	WNT5A	wingless-type MMTV integration site family, member 5A
chr16_+_86544104	0.588	NM_001451	FOXF1	forkhead box F1
chr5_-_150521200	0.584	NM_001193544	ANXA6	annexin A6
chr11_-_111782447	0.577	NM_001885	CRYAB	crystallin, alpha B
chr2_+_102770401	0.566	NM_000877	IL1R1	interleukin 1 receptor, type I
chr19_+_54057898	0.563	NM_001253801	ZNF331	zinc finger protein 331
chr12_+_7167979	0.561	NM_001734 NM_201442	C1S	complement component 1, s subcomponent
chr13_-_114538953	0.558	NM_001143945	GAS6	growth arrest-specific 6
chr7_+_45927958	0.543	NM_000596	IGFBP1	insulin-like growth factor binding protein 1
chr4_+_41258941	0.542		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr16_-_28634873	0.537	NM_177536	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chrX_+_99899162	0.531	NM_014467	SRPX2	sushi-repeat containing protein, X-linked 2
chr19_-_53758107	0.528	NM_182609	ZNF677	zinc finger protein 677
chr8_+_97505876	0.525	NM_002998	SDC2	syndecan 2
chr8_-_93107442	0.525	NM_001198629 NM_001198630 NM_001198632 NM_175635	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr19_-_8642232	0.524		MYO1F	myosin IF
chr19_-_48752921	0.524	NM_001184901 NM_001184903 NM_014959	CARD8	caspase recruitment domain family, member 8
chr17_-_5404304	0.522	NM_001162371	LOC728392	uncharacterized LOC728392
chr20_-_23618382	0.518	NM_000099	CST3	cystatin C
chr19_-_52227220	0.513	NM_001523	HAS1	hyaluronan synthase 1
chr12_+_108909049	0.502	NM_007076	FICD	FIC domain containing
chr12_-_9268475	0.493		A2M	alpha-2-macroglobulin
chrX_+_54835492	0.490	NM_201222	MAGED2	melanoma antigen family D, 2
chr11_-_27741192	0.486	NM_001143807	BDNF	brain-derived neurotrophic factor
chr3_-_127541160	0.485	NM_007283	MGLL	monoglyceride lipase
chr1_+_150245182	0.484	NM_024579	C1orf54	chromosome 1 open reading frame 54
chr3_+_51422691	0.477	NM_006010	MANF	mesencephalic astrocyte-derived neurotrophic factor
chrX_-_119603136	0.476		LAMP2	lysosomal-associated membrane protein 2
chrX_-_119603068	0.471		LAMP2	lysosomal-associated membrane protein 2
chr8_+_26371461	0.468	NM_001197293	DPYSL2	dihydropyrimidinase-like 2
chrX_-_130423387	0.463	NM_001170961 NM_001170962 NM_001555 NM_205833	IGSF1	immunoglobulin superfamily, member 1
chrX_+_102631267	0.459	NM_206915 NM_206917	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr2_-_242447449	0.458		STK25	serine/threonine kinase 25
chr10_+_114135937	0.455	NM_016234	ACSL5	acyl-CoA synthetase long-chain family member 5
chr7_-_81399286	0.448	NM_000601 NM_001010931 NM_001010932 NM_001010933 NM_001010934	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)
chr11_-_35440514	0.441		SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chrX_-_128657381	0.436		SMARCA1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr10_+_114710785	0.436		TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr13_-_33859835	0.433	NM_178006	STARD13	StAR-related lipid transfer (START) domain containing 13
chr3_+_51422716	0.431		MANF	mesencephalic astrocyte-derived neurotrophic factor
chr12_-_9268440	0.430		A2M	alpha-2-macroglobulin
chr1_-_89591685	0.429	NM_004120	GBP2	guanylate binding protein 2, interferon-inducible
chr1_+_203444955	0.418		PRELP	proline/arginine-rich end leucine-rich repeat protein
chr1_-_153600714	0.412	NM_005979	S100A13	S100 calcium binding protein A13
chr2_-_47168902	0.407	NM_001171508 NM_001171511	MCFD2	multiple coagulation factor deficiency 2
chr13_-_49107250	0.402	NM_001268	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr10_+_114135965	0.401		ACSL5	acyl-CoA synthetase long-chain family member 5
chr16_+_69220940	0.396	NM_006750	SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr15_-_75017710	0.395	NM_000499	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1
chr19_+_41725098	0.387	NM_001699 NM_021913	AXL	AXL receptor tyrosine kinase
chr10_-_74856590	0.379		P4HA1	prolyl 4-hydroxylase, alpha polypeptide I
chrX_-_130423199	0.377		IGSF1	immunoglobulin superfamily, member 1
chr1_-_146696896	0.371		FMO5	flavin containing monooxygenase 5
chr2_+_138721807	0.371	NM_001024074 NM_001024075 NM_006895	HNMT	histamine N-methyltransferase
chr19_-_53757940	0.361		ZNF677	zinc finger protein 677
chr4_+_55523906	0.357	NM_000222 NM_001093772	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chrX_-_104465349	0.354	NM_031274	TEX13A	testis expressed 13A
chr2_+_219283809	0.353	NM_007127	VIL1	villin 1
chr6_+_31588524	0.351		PRRC2A	proline-rich coiled-coil 2A
chr3_+_105085553	0.347	NM_001243280 NM_001243281 NM_001243283 NM_001627	ALCAM	activated leukocyte cell adhesion molecule
chr17_-_34756980	0.342	NM_001123392	TBC1D3C TBC1D3G TBC1D3 TBC1D3H	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3H
chr11_-_117102810	0.340	NM_004716	PCSK7	proprotein convertase subtilisin/kexin type 7
chr2_+_17721806	0.338	NM_003385	VSNL1	visinin-like 1
chrX_-_38079980	0.337	NM_001170750 NM_001170751 NM_001170752 NM_006307	SRPX	sushi-repeat containing protein, X-linked
chr17_-_36348585	0.335	NM_001123391 NM_032258	TBC1D3C TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3 TBC1 domain family, member 3F
chr2_+_201473942	0.334		AOX1	aldehyde oxidase 1
chr3_+_23986735	0.333	NM_005126	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr17_+_36283959	0.333	NM_001123391 NM_032258	TBC1D3C TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3 TBC1 domain family, member 3F
chr1_-_155177685	0.332	NM_001252607 NM_001252608 NM_007112	THBS3	thrombospondin 3
chr16_-_31085503	0.331	NM_024706	ZNF668	zinc finger protein 668
chr12_-_6798528	0.331	NM_133476	ZNF384	zinc finger protein 384
chrX_+_102631408	0.330		NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr2_-_211179765	0.329	NM_079420	MYL1	myosin, light chain 1, alkali; skeletal, fast
chr13_-_49107357	0.320		RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr6_-_24877453	0.320	NM_015864	FAM65B	family with sequence similarity 65, member B
chr6_-_6320875	0.312		F13A1	coagulation factor XIII, A1 polypeptide
chr12_+_56915587	0.307	NM_002898	RBMS2	RNA binding motif, single stranded interacting protein 2
chrX_+_149531439	0.305	NM_001177465	MAMLD1	mastermind-like domain containing 1
chr1_-_153599969	0.299	NM_001024211	S100A13	S100 calcium binding protein A13
chr17_+_39845142	0.296		EIF1	eukaryotic translation initiation factor 1
chr5_-_151066445	0.295		SPARC	secreted protein, acidic, cysteine-rich (osteonectin)
chr3_+_50304989	0.292	NM_001005914 NM_004636	SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr1_+_203444882	0.292	NM_002725 NM_201348	PRELP	proline/arginine-rich end leucine-rich repeat protein
chr2_-_216300444	0.292		FN1	fibronectin 1
chr1_-_203154304	0.290		CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr17_+_42148097	0.281	NM_138387	G6PC3	glucose 6 phosphatase, catalytic, 3
chr4_+_74281884	0.279		ALB	albumin
chr17_-_20946088	0.279	NM_015276	USP22	ubiquitin specific peptidase 22
chr20_+_25176333	0.277	NM_001114089 NM_001247	ENTPD6	ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chrX_+_102632108	0.277	NM_014380	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr16_-_49860917	0.276	NM_015069	ZNF423	zinc finger protein 423
chr3_-_58522873	0.275	NM_003500	ACOX2	acyl-CoA oxidase 2, branched chain
chr17_-_34503914	0.274	NM_001001417	TBC1D3B TBC1D3C TBC1D3G	TBC1 domain family, member 3B TBC1 domain family, member 3C TBC1 domain family, member 3G
chr7_-_94285477	0.272	NM_001099400 NM_001099401 NM_003919	SGCE	sarcoglycan, epsilon
chr7_-_140302311	0.270	NM_015689	DENND2A	DENN/MADD domain containing 2A
chr16_-_89556886	0.269	NM_013275	ANKRD11	ankyrin repeat domain 11
chr2_+_17721983	0.269		VSNL1	visinin-like 1
chr9_-_4742042	0.267	NM_001199853	AK3	adenylate kinase 3
chr17_-_26697293	0.264		VTN	vitronectin
chr10_-_74856656	0.264	NM_000917 NM_001017962 NM_001142595 NM_001142596	P4HA1	prolyl 4-hydroxylase, alpha polypeptide I
chr3_+_49027281	0.262	NM_177938 NM_177939	P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr3_+_11178778	0.261	NM_001098213	HRH1	histamine receptor H1
chrX_-_119603155	0.260	NM_001122606 NM_002294 NM_013995	LAMP2	lysosomal-associated membrane protein 2
chr10_+_123754141	0.257		TACC2	transforming, acidic coiled-coil containing protein 2
chr7_-_94285426	0.256		SGCE	sarcoglycan, epsilon
chr20_-_44455932	0.255	NM_003279	TNNC2	troponin C type 2 (fast)
chr1_-_184723952	0.255		EDEM3	ER degradation enhancer, mannosidase alpha-like 3
chrX_+_102883891	0.255	NM_001006639 NM_004780	TCEAL1	transcription elongation factor A (SII)-like 1
chr5_-_1112106	0.255	NM_006598	SLC12A7	solute carrier family 12 (potassium/chloride transporters), member 7
chr14_-_23904849	0.254	NM_000257	MYH7	myosin, heavy chain 7, cardiac muscle, beta
chr13_-_45048436	0.253	NM_001243798	TSC22D1	TSC22 domain family, member 1
chr1_+_162602198	0.253	NM_001014796 NM_006182	DDR2	discoidin domain receptor tyrosine kinase 2
chr17_+_7623038	0.253	NM_020877	DNAH2	dynein, axonemal, heavy chain 2
chr1_+_82266081	0.251	NM_012302	LPHN2	latrophilin 2
chr10_+_102295700	0.250		HIF1AN	hypoxia inducible factor 1, alpha subunit inhibitor
chr14_-_94844881	0.245		SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr19_+_34745452	0.244	NM_014686	KIAA0355	KIAA0355
chr7_+_100199881	0.243	NM_002593	PCOLCE	procollagen C-endopeptidase enhancer
chr9_-_4741798	0.237	NM_001199855	AK3	adenylate kinase 3
chr3_-_114478117	0.235	NM_001164344 NM_001164345	ZBTB20	zinc finger and BTB domain containing 20
chr15_-_85201793	0.234	NM_021077 NM_205858	NMB	neuromedin B
chr9_+_131388167	0.231		SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr9_-_94185959	0.229		NFIL3	nuclear factor, interleukin 3 regulated
chr17_-_76921076	0.229		TIMP2	TIMP metallopeptidase inhibitor 2
chr10_+_102295572	0.228	NM_017902	HIF1AN	hypoxia inducible factor 1, alpha subunit inhibitor
chr1_+_148577356	0.227	NM_001102663	NBPF15 NBPF16	neuroblastoma breakpoint family, member 15 neuroblastoma breakpoint family, member 16
chr1_+_144614958	0.225	NM_001037675	NBPF9 NBPF8	neuroblastoma breakpoint family, member 9 neuroblastoma breakpoint family, member 8
chr5_+_179247911	0.222		SQSTM1	sequestosome 1
chr3_+_186330711	0.221		AHSG	alpha-2-HS-glycoprotein
chr2_-_242448000	0.220	NM_006374	STK25	serine/threonine kinase 25
chr11_-_117102758	0.216		PCSK7	proprotein convertase subtilisin/kexin type 7
chr2_-_227664330	0.216		IRS1	insulin receptor substrate 1
chr15_+_33010174	0.215	NM_001191322 NM_001191323 NM_013372	GREM1	gremlin 1
chrX_-_64196268	0.214	NM_001178033 NM_018684	ZC4H2	zinc finger, C4H2 domain containing
chr4_-_77134689	0.213		SCARB2	scavenger receptor class B, member 2
chr17_-_46115135	0.212	NM_016429	COPZ2	coatomer protein complex, subunit zeta 2
chr17_-_34591958	0.212	NM_001001418	TBC1D3C TBC1D3G	TBC1 domain family, member 3C TBC1 domain family, member 3G
chr9_-_86571652	0.209	NM_032307	C9orf64	chromosome 9 open reading frame 64
chr14_-_23822025	0.209	NM_016609	SLC22A17	solute carrier family 22, member 17
chr14_-_23285011	0.208	NM_001126105	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr2_+_170335948	0.206	NM_152384	BBS5	Bardet-Biedl syndrome 5
chrX_+_7137471	0.205	NM_000351	STS	steroid sulfatase (microsomal), isozyme S
chr6_+_36646455	0.202	NM_000389 NM_001220778	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr8_+_38585703	0.201	NM_001146216	TACC1	transforming, acidic coiled-coil containing protein 1
chr22_-_37608352	0.201	NM_001051	SSTR3	somatostatin receptor 3

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
31.67	1.29e-02	GO:0072376	protein activation cascade
84.37	3.04e-02	GO:0050996	positive regulation of lipid catabolic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
5.37	3.22e-06	GO:0005576	extracellular region
6.85	3.90e-05	GO:0044421	extracellular region part
7.66	8.29e-05	GO:0005615	extracellular space

Nothing significant found in function category.